5-MeO-DMT: Difference between revisions
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[[Image:5meodmtfreebase.png|thumb|right|300px|''5-MeO-DMT Molecule'']] | |||
== Brief overview - What is 5-MeO-DMT? == | == Brief overview - What is 5-MeO-DMT? == | ||
5-MeO-DMT is a potent naturally occuring psychedelic alkaloid. | |||
== Chemical and physical properties == | == Chemical and physical properties == | ||
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== Extraction teks == | == Extraction teks == | ||
Any typical extraction teks for [[DMT]] should potentially extract 5-MeO-DMT (but it will also extract DMT together). | |||
== Dosages and consumption methods == | == Dosages and consumption methods == | ||
5-MeO-DMT is around 5 times more potent than DMT by weight. | |||
Smoked, dosage is around 5-15mg. | |||
Oral, according to Jonathan Ott, 30mg are active without the need for MAOIs. Mixing with MAOIs, it will be 3 times stronger, so a dosage will be around 10mg. There is some concern about 5-MeO-DMT's oral ingestion safety, and it might be related with individual metabolism differencescheck [https://www.dmt-nexus.me/forum/default.aspx?g=posts&m=153445#post153445 this] thread for more info. If you are consuming 5-MeO-DMT orally for the first time, specially with MAOIs, start VERY low and raise your dosage gradually. | |||
Insufflated, 5-20mg (Erowid) | |||
== History of usage == | == History of usage == | ||
Revision as of 10:14, 8 November 2011
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Note: | This page has been transcluded to The Nexian DMT Handbook under the 5-MeO-DMT section or other locations within or without the handbook. Please markup in consideration of this. The top section header is to remain in place as a reference for subsequent section headers and to allow easy editing directly from the handbook. |
Brief overview - What is 5-MeO-DMT?
5-MeO-DMT is a potent naturally occuring psychedelic alkaloid.
Chemical and physical properties
For solubility, melting point, etc, check the 5-MeO-DMT Chemical and Physical Properties WIKI
Effects
Pharmacology, toxicity and general safety
Life-forms containing 5-MeO-DMT
Extraction teks
Any typical extraction teks for DMT should potentially extract 5-MeO-DMT (but it will also extract DMT together).
Dosages and consumption methods
5-MeO-DMT is around 5 times more potent than DMT by weight.
Smoked, dosage is around 5-15mg.
Oral, according to Jonathan Ott, 30mg are active without the need for MAOIs. Mixing with MAOIs, it will be 3 times stronger, so a dosage will be around 10mg. There is some concern about 5-MeO-DMT's oral ingestion safety, and it might be related with individual metabolism differencescheck this thread for more info. If you are consuming 5-MeO-DMT orally for the first time, specially with MAOIs, start VERY low and raise your dosage gradually.
Insufflated, 5-20mg (Erowid)
History of usage
Analysis of 5-MeO-DMT
GC-MS
Retention time: 12.946 (System used)
Other info: 5-MeO-DMT: EI/MS (m/z, %): 218 (M+ , 10), 160 (6.3), 145 (2.5), 117 (5.0), 58 (100), 42 (4). (Takahashi 2008)
InfraRed
5-MeO-DMT freebase
NMR
1H NMR (400 MHz, D2O) δ ppm 7.47 (d, J=8.90 Hz, 1 H) 7.32 (s, 1 H) 7.20 (d, J=2.45 Hz, 1 H) 6.97 (dd, J=8.90, 2.45 Hz, 1 H) 3.91 (s, 3 H) 3.46 (t, J=7.43 Hz, 2 H) 3.20 (t, J=7.43 Hz, 2 H) 2.92 (s, 6 H).
(Source: Microgram Bulletin Vol. 3, Pg 8)
Other info: 1 H-NMR (CDCl , δ): 2.34 (6 H, s), 2.63 (2 H, m), 2.91 (2 H, m), 3.86 (3 H, s), 6.85 (1 H, dd, J = 2.3, 8.6 Hz), 6.98 (1 H, br d, J = 2.3 Hz), 7.05 (1 H, d, J = 2.3 Hz), 7.22 (1 H, d, J = 8.6 Hz). 13 C-NMR (CDCl3 , δ): 23.7, 45.4, 56.0, 60.1, 100.8, 111.8, 112.1, 113.9, 122.3, 127.8, 131.5, 153.9. (Takahashi 2008)
