1P-ETH-LAD: Difference between revisions

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* Psychedelic
* Psychedelic
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* Anecdotal report of being indistinguishable from LSD.<ref>[http://www.bluelight.org/vb/threads/745848-The-Big-amp-Dandy-1P-ETH-LAD-%281-propionyl-lysergic-acid-diethylamide%29-Thread bluelight.org: The Big & Dandy 1P-ETH-LAD (1-propionyl-lysergic acid diethylamide) Thread]</ref>
* Anecdotal report of being comparable to [[AL-LAD]].<ref>http://www.bluelight.org/vb/threads/781229-1P-Eth-Lad-quot-The-Third-Journey-quot</ref>
* Possible main effects: open and closed eye visuals, euphoria, change in perception of time.
* Possible main effects: open and closed eye visuals, euphoria, change in perception of time.
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== Chemical and physical properties ==
== Chemical and physical properties ==
[[Image:1P-ETH-LAD.png|right|thumb|200px|1P-ETH-LAD]]
[[Image:1P-ETH-LAD.png|right|thumb|200px|1P-ETH-LAD]]
* Systematic (IUPAC) name: (6aR,9R)-4-propionyl-N,N-diethyl-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
* Systematic (IUPAC) name: (6aR,9R)-4-propionyl-N,N-diethyl-7-ethyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
* Synonym: 1-Propionyl-lysergic acid diethylamide
* Synonym: 1P-ETH-LAD, 1-propionyl-6-ethyl-6-nor-lysergic acid diethyamide
----
* Formula: C24H31N3O2
* Salt: L-tartrate
* Appearance: Off-white crystalline powder
* Paper: High absorbancy blotting paper (perforated)
* Square Perforation: 9x9mm
* Quantity of 1P-ETH-LAD/Square: 100mcg


From an old Wikipedia draft regarding 1P-LSD (1P-METH-LAD):<ref>https://en.wikipedia.org/w/index.php?title=Draft:1P-ETH-LAD&oldid=647406505</ref><br />
== Effects ==
It's likely that the substance behaves like [[1P-LSD]] and [[ETH-LAD]].<ref>http://www.bluelight.org/vb/threads/781229-1P-Eth-Lad-quot-The-Third-Journey-quot</ref> Don't start with doses over 100µg, it's likely that the threshold of this material is 1/4 of a blot, which is 25µg.


''Sharing a strong structural similarity with ALD-52, the chemical purportedly used in the 1960's Orange Sunshine 1P-ETH-LAD follows the less common path of modifying the 1- position on the LSD molecule which in the past has been avoided due to unpredictable results or lack of activity.<ref>http://chemistry.mdma.ch/hiveboard/palladium/pdf/Ergot%20-%20The%20Genus%20Claviceps%20(1999)/TF3168ch8.pdf</ref>
''Lots of debate is surrounding the action of 1P-ETH-LAD and is unclear exactly how the chemical is functional with an unconfirmed quote from David E. Nichols believing the chemical should be inactive while most other speculation believing it would simply follow the same metabolic path as ALD-52 and undergo conversion in vivo to LSD.''
''"I am sure that the 1-propionyl would also hydrolyze off of an indole, but I don't know whether in vivo conditions would work.  In a chemistry lab, you can get off an N-benzoyl, so an N-propionyl will probably come off too.  But in the body?  I don't know the answer to that.  The compound would not be active as the N-propionyl however.  Way that LSD docks into the 5-HT2A receptor, the indole NH hydrogen bonds to serine 5.46.  With the propionyl, it won't fit into the receptor."<ref>http://www.shroomery.org/forums/showflat.php/Number/21106929#21106929</ref>''
<!--== Brief overview - What is 1P-ETH-LAD? ==
<!--== Brief overview - What is 1P-ETH-LAD? ==


== Effects ==


== Pharmacology, toxicity and general safety ==
== Pharmacology, toxicity and general safety ==

Latest revision as of 10:50, 28 January 2016

Safety profile
Category:
  • Psychedelic
Main effects:
  • Anecdotal report of being comparable to AL-LAD.[1]
  • Possible main effects: open and closed eye visuals, euphoria, change in perception of time.
Side effects:
  • Possible side effects: nausea, vasoconstriction, unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing
Health risks:
  • Possible mental side effects: paranoia, fear, and panic. Hallucinogen persisting perception disorder.
  • No other known specific physical risks at this time.
Important safety remarks:
  • 1P-ETH-LAD is a research chemical not mentioned in academic literature. The LD50 (median lethal dose) or long term / pharmacological / behavioral risks are not known.
  • 1P-ETH-LAD is likely a controlled substance analogue under US law if intended for human consumption.
  • This chemical is active in the microgram (µg) range. Please use caution when working with this substance, a calibrated milligram scale and liquid measurement are vital.
  • Do not ingest 1P-ETH-LAD when your mental or physical health is poor. Observe the set and setting.



Chemical and physical properties

1P-ETH-LAD
  • Systematic (IUPAC) name: (6aR,9R)-4-propionyl-N,N-diethyl-7-ethyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide
  • Synonym: 1P-ETH-LAD, 1-propionyl-6-ethyl-6-nor-lysergic acid diethyamide
  • Formula: C24H31N3O2
  • Salt: L-tartrate
  • Appearance: Off-white crystalline powder
  • Paper: High absorbancy blotting paper (perforated)
  • Square Perforation: 9x9mm
  • Quantity of 1P-ETH-LAD/Square: 100mcg

Effects

It's likely that the substance behaves like 1P-LSD and ETH-LAD.[2] Don't start with doses over 100µg, it's likely that the threshold of this material is 1/4 of a blot, which is 25µg.

Links

References

  1. ↑ http://www.bluelight.org/vb/threads/781229-1P-Eth-Lad-quot-The-Third-Journey-quot
  2. ↑ http://www.bluelight.org/vb/threads/781229-1P-Eth-Lad-quot-The-Third-Journey-quot
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