25I-NBOH - Revision history

Ufo: /* Links */

2014-04-19T13:26:59Z

Links

← Older revision		Revision as of 13:26, 19 April 2014
Line 25:		Line 25:
	==Links==		==Links==
	* bluelight.org: [http://www.bluelight.org/vb/threads/663416-The-Big-Dandy-25I-NBOH-Thread The Big Dandy 25I-NBOH Thread]		* bluelight.org: [http://www.bluelight.org/vb/threads/663416-The-Big-Dandy-25I-NBOH-Thread The Big Dandy 25I-NBOH Thread]
			* drugs-forum.com: [http://www.drugs-forum.com/forum/showthread.php?t=95632 25I-NBOH Experiences]
	* isomerdesign.com: [http://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=5379 25I-NBOH]		* isomerdesign.com: [http://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=5379 25I-NBOH]
	* wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]		* wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]
	* eve-rave.ch: [http://eve-rave.ch/Forum/viewtopic.php?f=53&t=32464 25i/c-nboh] (German)		* eve-rave.ch: [http://eve-rave.ch/Forum/viewtopic.php?f=53&t=32464 25i/c-nboh] (German)
	* drugs-forum.com: [http://www.drugs-forum.com/forum/showthread.php?t=95632 25I-NBOH Experiences]

	== Reference ==		== Reference ==

Ufo at 13:26, 19 April 2014

2014-04-19T13:26:20Z

← Older revision		Revision as of 13:26, 19 April 2014
Line 11:		Line 11:
	* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.		* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
	* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!		* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
	* Warning: This chemical is active in the '''microgram~~'''~~ (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''		* Warning: This chemical is active in the '''[https://en.wikipedia.org/wiki/Microgram microgram (µg)] range'''! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
	* Warning: Do not ingest 25I-NBOH while under the influence of a second medicine/substance/drug/MAOI!		* Warning: Do not ingest 25I-NBOH while '''under the influence of a second medicine/substance/drug/MAOI!'''
	* Warning: Do not ingest 25I-NBOH when your mental or physical health is poor. '''Observe the [https://en.wikipedia.org/wiki/Set_and_setting set and setting]!'''		* Warning: Do not ingest 25I-NBOH when your mental or physical health is poor. '''Observe the [https://en.wikipedia.org/wiki/Set_and_setting set and setting]!'''
	}}		}}
	'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [https://en.wikipedia.org/wiki/2C-I 2C-I]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to '''[[25x-NBOME\|25I-NBOMe]]''' with a Ki of 0.044 nM ('''sixteen times the potency of 2C-I''').<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref> Therefore treat ~~the~~ NBOH ~~series substances~~ like ~~the~~ NBOMe ~~series substances~~.		'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [https://en.wikipedia.org/wiki/2C-I 2C-I]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to '''[[25x-NBOME\|25I-NBOMe]]''' with a Ki of 0.044 nM ('''sixteen times the potency of 2C-I''').<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref> Therefore treat 25I-NBOH like you would treat 25I-NBOMe.

	It was discovered in 2006 by a team at Purdue University.		It was discovered in 2006 by a team at Purdue University.

	*Activity via '''[https://en.wikipedia.org/wiki/Sublingual_administration sublingual administration]''' or parenteral starts at well below one milligram (full activity at 500-700µg) and may be fatal in high doses!		*Activity via '''[https://en.wikipedia.org/wiki/Sublingual_administration sublingual administration]''' or parenteral starts at well below one milligram (full activity at 500-700µg) and '''<span style="color:#FF2020">may be fatal in high doses</span>'''!

	*Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.		*Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.

Ufo at 13:17, 19 April 2014

2014-04-19T13:17:49Z

Ufo at 13:04, 19 April 2014

2014-04-19T13:04:33Z

← Older revision		Revision as of 13:04, 19 April 2014
Line 13:		Line 13:
	* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''		* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
	* Do not ingest 25I-NBOH while under the influence of a second medicine/substance/drug/MAOI!		* Do not ingest 25I-NBOH while under the influence of a second medicine/substance/drug/MAOI!
			* Do not ingest 25I-NBOH when your mental or physical health is poor. '''Observe the [http://en.wikipedia.org/wiki/Set_and_setting set and setting]!'''
	}}		}}
	'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to 25I-NBOMe with a Ki of 0.044 nM, sixteen times the potency of 2C-I.<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref>		'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to 25I-NBOMe with a Ki of 0.044 nM, sixteen times the potency of 2C-I.<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref>

Ufo at 13:00, 19 April 2014

2014-04-19T13:00:47Z

← Older revision		Revision as of 13:00, 19 April 2014
Line 25:		Line 25:

	*Doses of more than three milligrams may produce seizures and doses of less than ten milligrams may be fatal (shown in other n-benzyl derivatives).		*Doses of more than three milligrams may produce seizures and doses of less than ten milligrams may be fatal (shown in other n-benzyl derivatives).


	==Links==		==Links==

Ufo at 13:00, 19 April 2014

2014-04-19T13:00:07Z

← Older revision		Revision as of 13:00, 19 April 2014
Line 12:		Line 12:
	* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!		* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
	* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''		* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
			* Do not ingest 25I-NBOH while under the influence of a second medicine/substance/drug/MAOI!
	}}		}}
	'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to 25I-NBOMe with a Ki of 0.044 nM, sixteen times the potency of 2C-I.<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref>		'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to 25I-NBOMe with a Ki of 0.044 nM, sixteen times the potency of 2C-I.<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref>

Ufo at 12:58, 19 April 2014

2014-04-19T12:58:25Z

← Older revision		Revision as of 12:58, 19 April 2014
Line 13:		Line 13:
	* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''		* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
	}}		}}
	'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor~~, similar to the better-known compound 25I-NBOMe~~, '''making it some twelve times the potency of 2C-I itself'''.		'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to 25I-NBOMe with a Ki of 0.044 nM, sixteen times the potency of 2C-I.<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref>

	It was discovered in 2006 by a team at Purdue University.		It was discovered in 2006 by a team at Purdue University.

Ufo at 12:50, 19 April 2014

2014-04-19T12:50:16Z

← Older revision		Revision as of 12:50, 19 April 2014
Line 16:		Line 16:

	It was discovered in 2006 by a team at Purdue University.		It was discovered in 2006 by a team at Purdue University.

			*Activity via sublingual or parenteral starts at well below one milligram (full activity at 500-700µg) and may be fatal in high doses.

			*Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.

			*Doses above one-two milligram(s) have produced profound effects including severe confusion, disorientation, and overwhelming visual distortions.

			*Doses of more than three milligrams may produce seizures and doses of less than ten milligrams may be fatal (shown in other n-benzyl derivatives).


	==Links==		==Links==

Ufo at 12:42, 19 April 2014

2014-04-19T12:42:38Z

← Older revision		Revision as of 12:42, 19 April 2014
Line 11:		Line 11:
	* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.		* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
	* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!		* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
	* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''		* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
	}}		}}
	'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, '''making it some twelve times the potency of 2C-I itself'''.		'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, '''making it some twelve times the potency of 2C-I itself'''.

Ufo at 12:42, 19 April 2014

2014-04-19T12:42:10Z

← Older revision		Revision as of 12:42, 19 April 2014
Line 5:		Line 5:
	* Open and closed eye visuals, euphoria, change in perception of time		* Open and closed eye visuals, euphoria, change in perception of time
	\|		\|
	* Nausea (possible), [http://en.wikipedia.org/wiki/Vasoconstriction vasoconstriction](mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible)		* Nausea (possible), [http://en.wikipedia.org/wiki/Vasoconstriction vasoconstriction](mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible), enlarged pupils
	\|		\|
	* paranoia (possible), fear (possible), panic (possible), [http://en.wikipedia.org/wiki/Dystonia dystonia] (rare), seizure (rare), death (rare)		* paranoia (possible), fear (possible), panic (possible), [http://en.wikipedia.org/wiki/Dystonia dystonia] (rare), seizure (rare), death (rare)

← Older revision		Revision as of 13:17, 19 April 2014
Line 5:		Line 5:
	* Open and closed eye visuals, euphoria, change in perception of time		* Open and closed eye visuals, euphoria, change in perception of time
	\|		\|
	* Nausea (possible), [~~http~~://en.wikipedia.org/wiki/Vasoconstriction vasoconstriction]~~(mostly when combined with other vasoconstricting substances like LSD)~~, unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible), enlarged pupils		* Nausea (possible), [https://en.wikipedia.org/wiki/Vasoconstriction vasoconstriction], unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible), enlarged pupils
	\|		\|
	* paranoia (possible), fear (possible), panic (possible), [~~http~~://en.wikipedia.org/wiki/Dystonia dystonia] (rare), seizure (rare), death (rare)		* paranoia (possible), fear (possible), panic (possible), [https://en.wikipedia.org/wiki/Dystonia dystonia] (rare), seizure (rare), death (rare)
	\|		\|
	* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.		* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
	* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!		* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
	* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''		* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
	* Do not ingest 25I-NBOH while under the influence of a second medicine/substance/drug/MAOI!		* Warning: Do not ingest 25I-NBOH while under the influence of a second medicine/substance/drug/MAOI!
	* Do not ingest 25I-NBOH when your mental or physical health is poor. '''Observe the [~~http~~://en.wikipedia.org/wiki/Set_and_setting set and setting]!'''		* Warning: Do not ingest 25I-NBOH when your mental or physical health is poor. '''Observe the [https://en.wikipedia.org/wiki/Set_and_setting set and setting]!'''
	}}		}}
	'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to 25I-NBOMe with a Ki of 0.044 nM, sixteen times the potency of 2C-I.<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref>		'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [https://en.wikipedia.org/wiki/2C-I 2C-I]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to '''[[25x-NBOME\|25I-NBOMe]]''' with a Ki of 0.044 nM ('''sixteen times the potency of 2C-I''').<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref> Therefore treat the NBOH series substances like the NBOMe series substances.

	It was discovered in 2006 by a team at Purdue University.		It was discovered in 2006 by a team at Purdue University.

	*Activity via sublingual or parenteral starts at well below one milligram (full activity at 500-700µg) and may be fatal in high doses.		*Activity via '''[https://en.wikipedia.org/wiki/Sublingual_administration sublingual administration]''' or parenteral starts at well below one milligram (full activity at 500-700µg) and may be fatal in high doses!

	*Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.		*Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.

	*Doses above one-two milligram(s) have produced profound effects including severe confusion, disorientation, and overwhelming visual distortions.

	*Doses of more than three milligrams may produce seizures and doses of less than ten milligrams may be fatal (shown in other n-benzyl derivatives).

	==Links==		==Links==