DMT-Nexus Wiki - User contributions [en]

25I-NBOH

2014-04-19T13:26:59Z

Ufo: /* Links */

{{Safety_profile
|
* Psychedelic
|
* Open and closed eye visuals, euphoria, change in perception of time
|
* Nausea (possible), [https://en.wikipedia.org/wiki/Vasoconstriction vasoconstriction], unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible), enlarged pupils
|
* paranoia (possible), fear (possible), panic (possible), [https://en.wikipedia.org/wiki/Dystonia dystonia] (rare), seizure (rare), death (rare)
|
* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
* Warning: This chemical is active in the '''[https://en.wikipedia.org/wiki/Microgram microgram (µg)] range'''! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
* Warning: Do not ingest 25I-NBOH while '''under the influence of a second medicine/substance/drug/MAOI!'''
* Warning: Do not ingest 25I-NBOH when your mental or physical health is poor. '''Observe the [https://en.wikipedia.org/wiki/Set_and_setting set and setting]!'''
}}
'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [https://en.wikipedia.org/wiki/2C-I 2C-I]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to '''[[25x-NBOME|25I-NBOMe]]''' with a Ki of 0.044 nM ('''sixteen times the potency of 2C-I''').<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref> Therefore treat 25I-NBOH like you would treat 25I-NBOMe.

It was discovered in 2006 by a team at Purdue University.

*Activity via '''[https://en.wikipedia.org/wiki/Sublingual_administration sublingual administration]''' or parenteral starts at well below one milligram (full activity at 500-700µg) and '''<span style="color:#FF2020">may be fatal in high doses</span>'''!

*Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.

==Links==
* bluelight.org: [http://www.bluelight.org/vb/threads/663416-The-Big-Dandy-25I-NBOH-Thread The Big Dandy 25I-NBOH Thread]
* drugs-forum.com: [http://www.drugs-forum.com/forum/showthread.php?t=95632 25I-NBOH Experiences]
* isomerdesign.com: [http://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=5379 25I-NBOH]
* wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]
* eve-rave.ch: [http://eve-rave.ch/Forum/viewtopic.php?f=53&t=32464 25i/c-nboh] (German)

== Reference ==
<references/>

[[Category:Research Chemicals]]

25I-NBOH

2014-04-19T13:26:20Z

Ufo:

{{Safety_profile
|
* Psychedelic
|
* Open and closed eye visuals, euphoria, change in perception of time
|
* Nausea (possible), [https://en.wikipedia.org/wiki/Vasoconstriction vasoconstriction], unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible), enlarged pupils
|
* paranoia (possible), fear (possible), panic (possible), [https://en.wikipedia.org/wiki/Dystonia dystonia] (rare), seizure (rare), death (rare)
|
* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
* Warning: This chemical is active in the '''[https://en.wikipedia.org/wiki/Microgram microgram (µg)] range'''! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
* Warning: Do not ingest 25I-NBOH while '''under the influence of a second medicine/substance/drug/MAOI!'''
* Warning: Do not ingest 25I-NBOH when your mental or physical health is poor. '''Observe the [https://en.wikipedia.org/wiki/Set_and_setting set and setting]!'''
}}
'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [https://en.wikipedia.org/wiki/2C-I 2C-I]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to '''[[25x-NBOME|25I-NBOMe]]''' with a Ki of 0.044 nM ('''sixteen times the potency of 2C-I''').<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref> Therefore treat 25I-NBOH like you would treat 25I-NBOMe.

It was discovered in 2006 by a team at Purdue University.

*Activity via '''[https://en.wikipedia.org/wiki/Sublingual_administration sublingual administration]''' or parenteral starts at well below one milligram (full activity at 500-700µg) and '''<span style="color:#FF2020">may be fatal in high doses</span>'''!

*Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.

==Links==
* bluelight.org: [http://www.bluelight.org/vb/threads/663416-The-Big-Dandy-25I-NBOH-Thread The Big Dandy 25I-NBOH Thread]
* isomerdesign.com: [http://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=5379 25I-NBOH]
* wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]
* eve-rave.ch: [http://eve-rave.ch/Forum/viewtopic.php?f=53&t=32464 25i/c-nboh] (German)
* drugs-forum.com: [http://www.drugs-forum.com/forum/showthread.php?t=95632 25I-NBOH Experiences]

== Reference ==
<references/>

[[Category:Research Chemicals]]

25I-NBOH

2014-04-19T13:17:49Z

Ufo:

{{Safety_profile
|
* Psychedelic
|
* Open and closed eye visuals, euphoria, change in perception of time
|
* Nausea (possible), [https://en.wikipedia.org/wiki/Vasoconstriction vasoconstriction], unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible), enlarged pupils
|
* paranoia (possible), fear (possible), panic (possible), [https://en.wikipedia.org/wiki/Dystonia dystonia] (rare), seizure (rare), death (rare)
|
* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
* Warning: Do not ingest 25I-NBOH while under the influence of a second medicine/substance/drug/MAOI!
* Warning: Do not ingest 25I-NBOH when your mental or physical health is poor. '''Observe the [https://en.wikipedia.org/wiki/Set_and_setting set and setting]!'''
}}
'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [https://en.wikipedia.org/wiki/2C-I 2C-I]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to '''[[25x-NBOME|25I-NBOMe]]''' with a Ki of 0.044 nM ('''sixteen times the potency of 2C-I''').<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref> Therefore treat the NBOH series substances like the NBOMe series substances.

It was discovered in 2006 by a team at Purdue University.

*Activity via '''[https://en.wikipedia.org/wiki/Sublingual_administration sublingual administration]''' or parenteral starts at well below one milligram (full activity at 500-700µg) and may be fatal in high doses!

*Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.

==Links==
* bluelight.org: [http://www.bluelight.org/vb/threads/663416-The-Big-Dandy-25I-NBOH-Thread The Big Dandy 25I-NBOH Thread]
* isomerdesign.com: [http://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=5379 25I-NBOH]
* wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]
* eve-rave.ch: [http://eve-rave.ch/Forum/viewtopic.php?f=53&t=32464 25i/c-nboh] (German)
* drugs-forum.com: [http://www.drugs-forum.com/forum/showthread.php?t=95632 25I-NBOH Experiences]

== Reference ==
<references/>

[[Category:Research Chemicals]]

25I-NBOH

2014-04-19T13:04:33Z

Ufo:

{{Safety_profile
|
* Psychedelic
|
* Open and closed eye visuals, euphoria, change in perception of time
|
* Nausea (possible), [http://en.wikipedia.org/wiki/Vasoconstriction vasoconstriction](mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible), enlarged pupils
|
* paranoia (possible), fear (possible), panic (possible), [http://en.wikipedia.org/wiki/Dystonia dystonia] (rare), seizure (rare), death (rare)
|
* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
* Do not ingest 25I-NBOH while under the influence of a second medicine/substance/drug/MAOI!
* Do not ingest 25I-NBOH when your mental or physical health is poor. '''Observe the [http://en.wikipedia.org/wiki/Set_and_setting set and setting]!'''
}}
'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to 25I-NBOMe with a Ki of 0.044 nM, sixteen times the potency of 2C-I.<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref>

It was discovered in 2006 by a team at Purdue University.

*Activity via sublingual or parenteral starts at well below one milligram (full activity at 500-700µg) and may be fatal in high doses.

*Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.

*Doses above one-two milligram(s) have produced profound effects including severe confusion, disorientation, and overwhelming visual distortions.

*Doses of more than three milligrams may produce seizures and doses of less than ten milligrams may be fatal (shown in other n-benzyl derivatives).

==Links==
* bluelight.org: [http://www.bluelight.org/vb/threads/663416-The-Big-Dandy-25I-NBOH-Thread The Big Dandy 25I-NBOH Thread]
* isomerdesign.com: [http://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=5379 25I-NBOH]
* wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]
* eve-rave.ch: [http://eve-rave.ch/Forum/viewtopic.php?f=53&t=32464 25i/c-nboh] (German)
* drugs-forum.com: [http://www.drugs-forum.com/forum/showthread.php?t=95632 25I-NBOH Experiences]

== Reference ==
<references/>

[[Category:Research Chemicals]]

25I-NBOH

2014-04-19T13:00:47Z

Ufo:

{{Safety_profile
|
* Psychedelic
|
* Open and closed eye visuals, euphoria, change in perception of time
|
* Nausea (possible), [http://en.wikipedia.org/wiki/Vasoconstriction vasoconstriction](mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible), enlarged pupils
|
* paranoia (possible), fear (possible), panic (possible), [http://en.wikipedia.org/wiki/Dystonia dystonia] (rare), seizure (rare), death (rare)
|
* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
* Do not ingest 25I-NBOH while under the influence of a second medicine/substance/drug/MAOI!
}}
'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to 25I-NBOMe with a Ki of 0.044 nM, sixteen times the potency of 2C-I.<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref>

It was discovered in 2006 by a team at Purdue University.

*Activity via sublingual or parenteral starts at well below one milligram (full activity at 500-700µg) and may be fatal in high doses.

*Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.

*Doses above one-two milligram(s) have produced profound effects including severe confusion, disorientation, and overwhelming visual distortions.

*Doses of more than three milligrams may produce seizures and doses of less than ten milligrams may be fatal (shown in other n-benzyl derivatives).

==Links==
* bluelight.org: [http://www.bluelight.org/vb/threads/663416-The-Big-Dandy-25I-NBOH-Thread The Big Dandy 25I-NBOH Thread]
* isomerdesign.com: [http://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=5379 25I-NBOH]
* wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]
* eve-rave.ch: [http://eve-rave.ch/Forum/viewtopic.php?f=53&t=32464 25i/c-nboh] (German)
* drugs-forum.com: [http://www.drugs-forum.com/forum/showthread.php?t=95632 25I-NBOH Experiences]

== Reference ==
<references/>

[[Category:Research Chemicals]]

25I-NBOH

2014-04-19T13:00:07Z

Ufo:

{{Safety_profile
|
* Psychedelic
|
* Open and closed eye visuals, euphoria, change in perception of time
|
* Nausea (possible), [http://en.wikipedia.org/wiki/Vasoconstriction vasoconstriction](mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible), enlarged pupils
|
* paranoia (possible), fear (possible), panic (possible), [http://en.wikipedia.org/wiki/Dystonia dystonia] (rare), seizure (rare), death (rare)
|
* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
* Do not ingest 25I-NBOH while under the influence of a second medicine/substance/drug/MAOI!
}}
'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to 25I-NBOMe with a Ki of 0.044 nM, sixteen times the potency of 2C-I.<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref>

It was discovered in 2006 by a team at Purdue University.

*Activity via sublingual or parenteral starts at well below one milligram (full activity at 500-700µg) and may be fatal in high doses.

*Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.

*Doses above one-two milligram(s) have produced profound effects including severe confusion, disorientation, and overwhelming visual distortions.

*Doses of more than three milligrams may produce seizures and doses of less than ten milligrams may be fatal (shown in other n-benzyl derivatives).

==Links==
* bluelight.org: [http://www.bluelight.org/vb/threads/663416-The-Big-Dandy-25I-NBOH-Thread The Big Dandy 25I-NBOH Thread]
* isomerdesign.com: [http://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=5379 25I-NBOH]
* wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]
* eve-rave.ch: [http://eve-rave.ch/Forum/viewtopic.php?f=53&t=32464 25i/c-nboh] (German)
* drugs-forum.com: [http://www.drugs-forum.com/forum/showthread.php?t=95632 25I-NBOH Experiences]

== Reference ==
<references/>

[[Category:Research Chemicals]]

25I-NBOH

2014-04-19T12:58:25Z

Ufo:

{{Safety_profile
|
* Psychedelic
|
* Open and closed eye visuals, euphoria, change in perception of time
|
* Nausea (possible), [http://en.wikipedia.org/wiki/Vasoconstriction vasoconstriction](mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible), enlarged pupils
|
* paranoia (possible), fear (possible), panic (possible), [http://en.wikipedia.org/wiki/Dystonia dystonia] (rare), seizure (rare), death (rare)
|
* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
}}
'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, '''making it some twelve times the potency of 2C-I itself'''. In contrast to 25I-NBOMe with a Ki of 0.044 nM, sixteen times the potency of 2C-I.<ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]</ref><ref>wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOMe 25I-NBOMe]</ref>

It was discovered in 2006 by a team at Purdue University.

*Activity via sublingual or parenteral starts at well below one milligram (full activity at 500-700µg) and may be fatal in high doses.

*Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.

*Doses above one-two milligram(s) have produced profound effects including severe confusion, disorientation, and overwhelming visual distortions.

*Doses of more than three milligrams may produce seizures and doses of less than ten milligrams may be fatal (shown in other n-benzyl derivatives).

==Links==
* bluelight.org: [http://www.bluelight.org/vb/threads/663416-The-Big-Dandy-25I-NBOH-Thread The Big Dandy 25I-NBOH Thread]
* isomerdesign.com: [http://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=5379 25I-NBOH]
* wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]
* eve-rave.ch: [http://eve-rave.ch/Forum/viewtopic.php?f=53&t=32464 25i/c-nboh] (German)
* drugs-forum.com: [http://www.drugs-forum.com/forum/showthread.php?t=95632 25I-NBOH Experiences]

== Reference ==
<references/>

[[Category:Research Chemicals]]

25I-NBOH

2014-04-19T12:50:16Z

Ufo:

{{Safety_profile
|
* Psychedelic
|
* Open and closed eye visuals, euphoria, change in perception of time
|
* Nausea (possible), [http://en.wikipedia.org/wiki/Vasoconstriction vasoconstriction](mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible), enlarged pupils
|
* paranoia (possible), fear (possible), panic (possible), [http://en.wikipedia.org/wiki/Dystonia dystonia] (rare), seizure (rare), death (rare)
|
* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a calibrated milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
}}
'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, '''making it some twelve times the potency of 2C-I itself'''.

It was discovered in 2006 by a team at Purdue University.

*Activity via sublingual or parenteral starts at well below one milligram (full activity at 500-700µg) and may be fatal in high doses.

*Doses lower than one milligram have reported some visual and cognitive activity, though reports are not detailed/well-defined.

*Doses above one-two milligram(s) have produced profound effects including severe confusion, disorientation, and overwhelming visual distortions.

*Doses of more than three milligrams may produce seizures and doses of less than ten milligrams may be fatal (shown in other n-benzyl derivatives).

==Links==
* bluelight.org: [http://www.bluelight.org/vb/threads/663416-The-Big-Dandy-25I-NBOH-Thread The Big Dandy 25I-NBOH Thread]
* isomerdesign.com: [http://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=5379 25I-NBOH]
* wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]
* eve-rave.ch: [http://eve-rave.ch/Forum/viewtopic.php?f=53&t=32464 25i/c-nboh] (German)
* drugs-forum.com: [http://www.drugs-forum.com/forum/showthread.php?t=95632 25I-NBOH Experiences]

== Reference ==
<references/>

[[Category:Research Chemicals]]

25I-NBOH

2014-04-19T12:42:38Z

Ufo:

25I-NBOH

2014-04-19T12:42:10Z

Ufo:

25I-NBOH

2014-04-19T12:40:37Z

Ufo: /* Links */

25I-NBOH

2014-04-19T12:34:30Z

Ufo:

25I-NBOH

2014-04-19T12:33:55Z

Ufo:

25I-NBOH

2014-04-19T12:31:20Z

Ufo:

{{Safety_profile
|
* Psychedelic
|
* Open and closed eye visuals, euphoria, change in perception of time
|
* Nausea (possible), vasoconstriction (mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing (possible)
|
* paranoia (possible), fear (possible), panic (possible), dystonia (rare), seizure (rare), death (rare)
|
* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
* Warning: This chemical is active in the '''microgram''' (µg) range! Please use extreme caution if working with this substance, a milligram scale and liquid measurement are VITAL! '''Please start with doses of 500µg or less!'''
}}
'''25I-NBOH''' (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, '''making it some twelve times the potency of 2C-I itself'''.

It was discovered in 2006 by a team at Purdue University.

==Links==
* bluelight.org: [http://www.bluelight.org/vb/threads/663416-The-Big-Dandy-25I-NBOH-Thread The Big Dandy 25I-NBOH Thread]
* isomerdesign.com: [http://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=5379 25I-NBOH]
* wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]

== Reference ==
<references/>

[[Category:Research Chemicals]]

25I-NBOH

2014-04-19T12:26:26Z

Ufo:

{{Safety_profile
|
* Psychedelic
|
* Open and closed eye visuals, euphoria, change in perception of time
|
* Nausea, vasoconstriction (mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing
|
* paranoia, fear, and panic, dystonia (rare), seizure (rare), death (rare)
|
* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
* Warning: This chemical is active in the microgram (µg) range! Please use extreme caution if working with this substance, a milligram scale and liquid measurement are VITAL! Please start with doses of 500µg or less!
}}
25I-NBOH (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, '''making it some twelve times the potency of 2C-I itself'''.

It was discovered in 2006 by a team at Purdue University.

==Links==
* bluelight.org: [http://www.bluelight.org/vb/threads/663416-The-Big-Dandy-25I-NBOH-Thread The Big Dandy 25I-NBOH Thread]
* isomerdesign.com: [http://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=5379 25I-NBOH]
* wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]

== Reference ==
<references/>

[[Category:Research Chemicals]]

25I-NBOH

2014-04-19T12:25:31Z

Ufo: /* Links */

{{Safety_profile
|
* Psychedelic
|
* Open and closed eye visuals, euphoria, change in perception of time
|
* Nausea, vasoconstriction (mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing
|
* paranoia, fear, and panic, dystonia (rare), seizure (rare), death (rare)
|
* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
* Warning: This chemical is active in the microgram (µg) range! Please use extreme caution if working with this substance, a milligram scale and liquid measurement are VITAL! Please start with doses of 500µg or less!
}}

25I-NBOH (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, making it some twelve times the potency of 2C-I itself. In vitro tests showed this compound acted as an agonist but animal studies have not been reported. While the N-benzyl derivatives of 2C-I were significantly increased in binding activity to 5HT2A receptor fragments, compared to 2C-I, the N-benzyl derivatives of DOI were less active, compared to DOI.

It was discovered in 2006 by a team at Purdue University.

==Links==
* bluelight.org: [http://www.bluelight.org/vb/threads/663416-The-Big-Dandy-25I-NBOH-Thread The Big Dandy 25I-NBOH Thread]
* isomerdesign.com: [http://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=5379 25I-NBOH]
* wikipedia.org: [https://en.wikipedia.org/wiki/25I-NBOH 25I-NBOH]

== Reference ==
<references/>

[[Category:Research Chemicals]]

25I-NBOH

2014-04-19T12:23:37Z

Ufo:

{{Safety_profile
|
* Psychedelic
|
* Open and closed eye visuals, euphoria, change in perception of time
|
* Nausea, vasoconstriction (mostly when combined with other vasoconstricting substances like LSD), unusual body sensations (facial flushing, chills, goosebumps, body energy), slight increase in heart rate, difficulty focusing
|
* paranoia, fear, and panic, dystonia (rare), seizure (rare), death (rare)
|
* 25I-NBOH is a very new substance, with little known about its pharmacological or behavioral risks. The LD50 (median lethal dose) is not known.
* Elaborate studies on this substance have not been performed, so long term effects are UNKNOWN!
* Warning: This chemical is active in the microgram (µg) range! Please use extreme caution if working with this substance, a milligram scale and liquid measurement are VITAL! Please start with doses of 500µg or less!
}}

25I-NBOH (NBOH-2CI, Cimbi-27) is a derivative of the phenethylamine derived hallucinogen [[2C-I]]. It acts as a potent agonist for the 5HT2A receptor, with a Ki of 0.061nM at the human 5HT2A receptor, similar to the better-known compound 25I-NBOMe, making it some twelve times the potency of 2C-I itself. In vitro tests showed this compound acted as an agonist but animal studies have not been reported. While the N-benzyl derivatives of 2C-I were significantly increased in binding activity to 5HT2A receptor fragments, compared to 2C-I, the N-benzyl derivatives of DOI were less active, compared to DOI.

It was discovered in 2006 by a team at Purdue University.

==Links==
* bluelight.org: [http://www.bluelight.org/vb/threads/663416-The-Big-Dandy-25I-NBOH-Thread The Big Dandy 25I-NBOH Thread]
* isomerdesign.com: [http://isomerdesign.com/PiHKAL/explore.php?domain=pk&id=5379 25I-NBOH]

== Reference ==
<references/>

[[Category:Research Chemicals]]

25I-NBOH

2014-04-19T12:22:06Z

Ufo: Created page with "{{Safety_profile | * Psychedelic | * Open and closed eye visuals, euphoria, change in perception of time | * Nausea, vasoconstriction (mostly when combined with other vasocons..."